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| Title: | Oxidative Cross-Dehydrogenative C-H Bond Amination of Imidazo[1,2-a]pyridines in Aqueous Media Under Metal-free Conditions |
| Authors: | Sarothiya, Durgesh Kshirsagar, Umesh Achyutrao |
| Keywords: | CDC;Green solvent;Heterocycles;Metal Free;Oxidative coupling |
| Issue Date: | 2024 |
| Publisher: | Georg Thieme Verlag |
| Citation: | Sarothiya, D., & Kshirsagar, U. (2024). Oxidative Cross-Dehydrogenative C-H Bond Amination of Imidazo[1,2-a]pyridines in Aqueous Media Under Metal-free Conditions. Synthesis (Germany). https://doi.org/10.1055/a-2348-4764 |
| Abstract: | The metal-free direct oxidative cross-dehydrogenative C-H bond amination of imidazopyridines with pyrazole in water as solvent has been developed under K2S2O8-promoted mild conditions. This strategy applies to variable imidazoheterocycles to give amination products in moderate to good yield. The described protocol also offers scale-up synthesis for the construction of C-N bonds, which makes it suitable for the synthesis of biologically active compounds and pharmaceuticals. © 2024 Georg Thieme Verlag. All rights reserved. |
| URI: | https://doi.org/10.1055/a-2348-4764 https://dspace.iiti.ac.in/handle/123456789/14228 |
| ISSN: | 0039-7881 |
| Type of Material: | Journal Article |
| Appears in Collections: | Department of Chemistry |
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