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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Patidar, Pramod | en_US |
| dc.contributor.author | Bharti, Shreya | en_US |
| dc.contributor.author | Baig, Mirza Saqib | en_US |
| dc.date.accessioned | 2024-10-08T11:09:22Z | - |
| dc.date.available | 2024-10-08T11:09:22Z | - |
| dc.date.issued | 2024 | - |
| dc.identifier.citation | Patidar, P., Hirani, N., Bharti, S., & Baig, M. S. (2024). Key regulators of hepatic stellate cell activation in alcohol liver Disease: A comprehensive review. International Immunopharmacology. Scopus. https://doi.org/10.1016/j.intimp.2024.112938 | en_US |
| dc.identifier.issn | 1567-5769 | - |
| dc.identifier.other | EID(2-s2.0-85201467450) | - |
| dc.identifier.uri | https://doi.org/10.1016/j.intimp.2024.112938 | - |
| dc.identifier.uri | https://dspace.iiti.ac.in/handle/123456789/14575 | - |
| dc.description.abstract | Alcoholic liver disease (ALD) is a broad category of disorders that begin with liver injury, lead to liver fibrosis, and ultimately conclude in alcohol-induced liver cirrhosis, the most chronic and irreversible liver damage. Liver fibrosis (LF) is a common pathological characteristic observed in most chronic liver inflammatory conditions that involve prolonged inflammation. In this review, we have summarized ethanol-mediated hepatic stellate cell (HSCs) activation and its role in liver fibrosis progression. We highlight important molecular mechanisms that are modulated by ethanol, play a role in the activation of HSCs and the progression of liver fibrosis and identifying potential targets to ameliorate liver fibrosis. © 2024 | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Elsevier B.V. | en_US |
| dc.source | International Immunopharmacology | en_US |
| dc.subject | Alcoholic Liver Disease (ALD) | en_US |
| dc.subject | Chronic Liver Disease (CLD) | en_US |
| dc.subject | Hepatic Stellate Cells (HSCs) | en_US |
| dc.subject | Liver Fibrosis (LF) | en_US |
| dc.title | Key regulators of hepatic stellate cell activation in alcohol liver Disease: A comprehensive review | en_US |
| dc.type | Review | en_US |
| Appears in Collections: | Department of Biosciences and Biomedical Engineering | |
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