Case study: COVID-19 severity in diabetic patients with and without seizure

Abstract

Comorbidities like diabetes play a critical role in COVID-19 pathology. Neurological manifestations of COVID-19 have been reported in multiple studies. It would be intriguing to investigate the influence of COVID-19 and diabetes on the nervous system. The chapter described the findings from two diabetic COVID-19 patients with and without seizure from the Indian subcontinent. In spite of several comorbid conditions, including altered kidney functions, patient-1 survived for a greater number of days than patient-2. The treatment regime included RAAS inhibitors to patient-1 and levetiracetam for patient-2, who displayed persistent seizures. The number of comorbidities may not ultimately govern the fate of SARS-CoV-2 infection and mortality, rather the severity of particular comorbidity may impact COVID-19 and a patient’s recovery. Additionally, it is imperative to identify if seizures in such patients appear due to altered blood sugar or prevailing epilepsy or SARS-CoV-2 infection. A speculated association of seizures and COVID-19 exists

however, there is a need to evaluate the influence of seizures during COVID-19 in the infected individual. © 2024 Elsevier Inc. All rights reserved, including those for text and data mining, AI training, and similar technologies.