Please use this identifier to cite or link to this item: https://dspace.iiti.ac.in/handle/123456789/8827
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dc.contributor.authorDudhe, Premanshen_US
dc.contributor.authorPathak, Biswarupen_US
dc.contributor.authorChelvam, Venkateshen_US
dc.date.accessioned2022-03-17T01:00:00Z-
dc.date.accessioned2022-03-21T11:29:56Z-
dc.date.available2022-03-17T01:00:00Z-
dc.date.available2022-03-21T11:29:56Z-
dc.date.issued2020-
dc.identifier.citationDudhe, P., Venkatasubbaiah, K., Pathak, B., & Chelvam, V. (2020). Serendipitous base catalysed condensation-heteroannulation of iminoesters: A regioselective route to the synthesis of 4,6-disubstituted 5-azaindoles. Organic and Biomolecular Chemistry, 18(8), 1582-1587. doi:10.1039/c9ob02657fen_US
dc.identifier.issn1477-0520-
dc.identifier.otherEID(2-s2.0-85080111126)-
dc.identifier.urihttps://doi.org/10.1039/c9ob02657f-
dc.identifier.urihttps://dspace.iiti.ac.in/handle/123456789/8827-
dc.description.abstractA serendipitous discovery of a novel one-pot synthesis of 4,6-disubstituted 5-azaindoles is reported herein. In the presence of Hunig's base, various N-substituted pyrrole-2-carboxaldehydes have been efficiently transformed into their corresponding 4,6-disubstituted 5-azaindoles through an imine mediated cascade condensation-heteroannulation. The synthetic value of the methodology is established by preparing a novel chemical analogue of a cannabinoid receptor type 2 (CB2) agonist. This journal is © 2020 The Royal Society of Chemistry.en_US
dc.language.isoenen_US
dc.publisherRoyal Society of Chemistryen_US
dc.sourceOrganic and Biomolecular Chemistryen_US
dc.subjectCondensationen_US
dc.subjectCannabinoid receptorsen_US
dc.subjectHeteroannulationen_US
dc.subjectN-substituted pyrrolesen_US
dc.subjectOne-pot synthesisen_US
dc.subjectRegioselective routesen_US
dc.subjectSerendipitous discoveryen_US
dc.subjectRegioselectivityen_US
dc.titleSerendipitous base catalysed condensation-heteroannulation of iminoesters: a regioselective route to the synthesis of 4,6-disubstituted 5-azaindolesen_US
dc.typeJournal Articleen_US
Appears in Collections:Department of Chemistry

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