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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Dudhe, Premansh | en_US |
dc.contributor.author | Pathak, Biswarup | en_US |
dc.contributor.author | Chelvam, Venkatesh | en_US |
dc.date.accessioned | 2022-03-17T01:00:00Z | - |
dc.date.accessioned | 2022-03-21T11:29:56Z | - |
dc.date.available | 2022-03-17T01:00:00Z | - |
dc.date.available | 2022-03-21T11:29:56Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | Dudhe, P., Venkatasubbaiah, K., Pathak, B., & Chelvam, V. (2020). Serendipitous base catalysed condensation-heteroannulation of iminoesters: A regioselective route to the synthesis of 4,6-disubstituted 5-azaindoles. Organic and Biomolecular Chemistry, 18(8), 1582-1587. doi:10.1039/c9ob02657f | en_US |
dc.identifier.issn | 1477-0520 | - |
dc.identifier.other | EID(2-s2.0-85080111126) | - |
dc.identifier.uri | https://doi.org/10.1039/c9ob02657f | - |
dc.identifier.uri | https://dspace.iiti.ac.in/handle/123456789/8827 | - |
dc.description.abstract | A serendipitous discovery of a novel one-pot synthesis of 4,6-disubstituted 5-azaindoles is reported herein. In the presence of Hunig's base, various N-substituted pyrrole-2-carboxaldehydes have been efficiently transformed into their corresponding 4,6-disubstituted 5-azaindoles through an imine mediated cascade condensation-heteroannulation. The synthetic value of the methodology is established by preparing a novel chemical analogue of a cannabinoid receptor type 2 (CB2) agonist. This journal is © 2020 The Royal Society of Chemistry. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Royal Society of Chemistry | en_US |
dc.source | Organic and Biomolecular Chemistry | en_US |
dc.subject | Condensation | en_US |
dc.subject | Cannabinoid receptors | en_US |
dc.subject | Heteroannulation | en_US |
dc.subject | N-substituted pyrroles | en_US |
dc.subject | One-pot synthesis | en_US |
dc.subject | Regioselective routes | en_US |
dc.subject | Serendipitous discovery | en_US |
dc.subject | Regioselectivity | en_US |
dc.title | Serendipitous base catalysed condensation-heteroannulation of iminoesters: a regioselective route to the synthesis of 4,6-disubstituted 5-azaindoles | en_US |
dc.type | Journal Article | en_US |
Appears in Collections: | Department of Chemistry |
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