Recent Developments in Direct C-H Functionalization of Quinoxalin-2(1 H)-ones via Radical Addition Processes

Abstract

This review article covers the recent developments in direct C-H functionalization of quinoxalin-2(1 H)-one derivatives via radical additions at the C3 position. Reaction types have been categorized depending on the kind of radical used, with representative examples and insightful mechanistic details provided. 1 Introduction 2 Reactions with Alkyl Radicals 3 Reactions with Acyl Radicals 4 Reactions with Aryl Radicals 5 Reactions with Perfluoroalkyl Radicals 6 Reactions with Alkoxycarbonyl Radicals 7 Reactions with Nitrogen Radicals 8 Reactions with Oxygen Radicals 9 Reactions with Phosphorus Radicals 10 Conclusion. © 2019 All rights reserved.