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Please use this identifier to cite or link to this item: https://dspace.iiti.ac.in/handle/123456789/9080
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dc.contributor.authorMobin, Shaikh M.en_US
dc.date.accessioned2022-03-17T01:00:00Z-
dc.date.accessioned2022-03-21T11:30:58Z-
dc.date.available2022-03-17T01:00:00Z-
dc.date.available2022-03-21T11:30:58Z-
dc.date.issued2018-
dc.identifier.citationKumari, P., Verma, S. K., & Mobin, S. M. (2018). Water soluble two-photon fluorescent organic probes for long-term imaging of lysosomes in live cells and tumor spheroids. Chemical Communications, 54(5), 539-542. doi:10.1039/c7cc07812aen_US
dc.identifier.issn1359-7345-
dc.identifier.otherEID(2-s2.0-85040542394)-
dc.identifier.urihttps://doi.org/10.1039/c7cc07812a-
dc.identifier.urihttps://dspace.iiti.ac.in/handle/123456789/9080-
dc.description.abstractThe morphological alteration of lysosomes is a powerful indicator of various pathological disorders. In this regard, we have designed and synthesized a new water soluble fluorescent Schiff-base ligand (L-lyso) containing two hydroxyl groups. L-lyso exhibits excellent two-photon properties with tracking of lysosomes in live cells as well as in 3D tumor spheroids. Furthermore, it can label lysosomes for more than 3 days. Thus, L-lyso has an edge over the commercially available expensive LysoTracker probes and also over other reported probes in terms of its long-term imaging, water solubility and facile synthesis. © 2018 The Royal Society of Chemistry.en_US
dc.language.isoenen_US
dc.publisherRoyal Society of Chemistryen_US
dc.sourceChemical Communicationsen_US
dc.subjectArticleen_US
dc.subjectbleachingen_US
dc.subjectcontrolled studyen_US
dc.subjectcrystallizationen_US
dc.subjectendocytosisen_US
dc.subjectflow cytometryen_US
dc.subjecthumanen_US
dc.subjecthuman cellen_US
dc.subjecthydrophilicityen_US
dc.subjectimage analysisen_US
dc.subjectlive cell imagingen_US
dc.subjectlysosomeen_US
dc.subjectmolecular probeen_US
dc.subjectmorphologyen_US
dc.subjectmultiphoton microscopyen_US
dc.subjectnuclear magnetic resonance spectroscopyen_US
dc.subjectoxidative phosphorylationen_US
dc.subjectprotein localizationen_US
dc.subjectsynthesisen_US
dc.subjecttumor spheroiden_US
dc.subjectwater soluble two photon fluorescent organic probeen_US
dc.subjectcell survivalen_US
dc.subjectchemical structureen_US
dc.subjectchemistryen_US
dc.subjectfluorescenceen_US
dc.subjectfluorescence imagingen_US
dc.subjectHeLa cell lineen_US
dc.subjectlysosomeen_US
dc.subjectmulticellular spheroiden_US
dc.subjectpathologyen_US
dc.subjectphotonen_US
dc.subjectsolubilityen_US
dc.subjectfluorescent dyeen_US
dc.subjectwateren_US
dc.subjectCell Survivalen_US
dc.subjectFluorescenceen_US
dc.subjectFluorescent Dyesen_US
dc.subjectHeLa Cellsen_US
dc.subjectHumansen_US
dc.subjectLysosomesen_US
dc.subjectMolecular Structureen_US
dc.subjectOptical Imagingen_US
dc.subjectPhotonsen_US
dc.subjectSolubilityen_US
dc.subjectSpheroids, Cellularen_US
dc.subjectWateren_US
dc.titleWater soluble two-photon fluorescent organic probes for long-term imaging of lysosomes in live cells and tumor spheroidsen_US
dc.typeJournal Articleen_US
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