Photoactivatable carbon dots as a label-free fluorescent probe for picric acid detection and light-induced bacterial inactivation

Abstract

The zero-dimensional carbon nanostructure known as carbon dots showed attractive attributes such as multicolour emission, very high quantum yield, up-conversion, very good aqueous solubility, eco-friendliness, and excellent biocompatibility. These outstanding features of the carbon dots have raised significant interest among the research community worldwide. In the current work, water-soluble nitrogen, silver, and gold co-doped bimetallic carbon dots (BCDs) were prepared using the one-pot hydrothermal method with citric acid as a sole carbon source. As prepared BCDs showed size in the range of 4–8 nm and excitation-independent emission behaviour with maximum emission observed at 427 nm. Additionally, these BCDs showed a very high quantum yield value of 50% and fluorescence lifetime value of 10.1 ns respectively. Interestingly, as prepared BCDs selectively sense picric acid (PA) by exhibiting “selective fluorescence turn-off” behaviour in the presence of PA with a limit of detection value (LOD) of 46 nM. Further, as prepared BCDs were explored for photodynamic therapy to inactivate bacterial growth in the presence of light (400–700 nm) by generating singlet oxygen. Thus as prepared BCDs offer lots of potentials to use a nanoprobe to detect picric acid in an aqueous medium and to design next-generation antibacterial materials. © 2022 Elsevier B.V.