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Title: | Synergistic Approach for Decarboxylative Ortho C-H Aroylation of 2-Aryl-pyrido[1,2-a]pyrimidin-4-ones and Thiazolopyrimidinones by Merging Palladium Catalysis with Photo-catalysis |
Authors: | Bhawale, Rajesh T. Sarothiya, Durgesh Kshirsagar, Umesh Achyutrao |
Issue Date: | 2022 |
Publisher: | John Wiley and Sons Inc |
Citation: | Bhawale, R. T., Sarothiya, D., & Kshirsagar, U. A. (2022). Synergistic Approach for Decarboxylative Ortho C−H Aroylation of 2‐Aryl‐pyrido[1,2‐a]pyrimidin‐4‐ones and Thiazolopyrimidinones by Merging Palladium Catalysis with Photocatalysis. Asian Journal of Organic Chemistry. https://doi.org/10.1002/ajoc.202200134 |
Abstract: | A mild and efficient synergistic approach for decarboxylative aroylation of 2-aryl-pyrido[1,2- a]pyrimidin-4-ones having intrinsic directing group has been developed by merging of palladium catalysis and photo-redox catalysis at room temperature. Therapeutically interesting aryl ketones of pyrido[1,2- a]pyrimidin-4-one have been synthesized in good to excellent yield with good functional group tolerance. © 2022 Wiley-VCH GmbH. |
URI: | https://doi.org/10.1002/ajoc.202200134 https://dspace.iiti.ac.in/handle/123456789/10487 |
ISSN: | 2193-5807 |
Type of Material: | Journal Article |
Appears in Collections: | Department of Chemistry |
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