Theranostic role of nanoparticles on cancer cells using photothermal therapy

Abstract

Cancer is a deadly disease with millions of deaths annually. Enormous trials are going on towards preventing and curing this disease and developing various therapies. Using anti-cancer drugs freely causes several side effects on healthy cells. So, nanoparticles can be used for control and targeted drug delivery. The critical requirement for early disease identification and diagnosis drives the advancement of imaging techniques and contrast agents. Nanoparticle based bioimaging can also be done for bioimaging of cancer. Photothermal therapy is a widely used therapy for treating cancer in which NIR laser light is used to increase the temperature due to which cell death can occur. Various photo agents are used for PTT including NIR dyes. Iron oxide is widely used for photothermal therapy. So, in this project, the aim is to synthesize a theranostic nanohybrid using gold-coated iron oxide nanoparticles and chitosan for photothermal therapy as well as bioimaging using MRI and X-ray