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https://dspace.iiti.ac.in/handle/123456789/4036
| Title: | Matrix Metalloproteinases (MMPs) in Liver Diseases |
| Authors: | Naim, Adnan Baig, Mirza Saqib |
| Keywords: | collagenase 3;gelatinase A;gelatinase B;interstitial collagenase;macrophage elastase;matrilysin;matrix metalloproteinase;matrix metalloproteinase 14;matrix metalloproteinase 15;matrix metalloproteinase 16;matrix metalloproteinase 17;matrix metalloproteinase 19;matrix metalloproteinase 20;matrix metalloproteinase 22;matrix metalloproteinase 23;matrix metalloproteinase 24;matrix metalloproteinase 25;matrix metalloproteinase 26;matrix metalloproteinase 28;neutrophil collagenase;stromelysin;stromelysin 2;stromelysin 3;unclassified drug;cell proliferation;hepatitis;human;liver cell;liver cell carcinoma;liver cirrhosis;liver disease;liver fibrosis;liver injury;liver ischemia;nonhuman;pathogenesis;priority journal;protein expression;reperfusion injury;Review |
| Issue Date: | 2017 |
| Publisher: | Elsevier B.V. |
| Citation: | Naim, A., Pan, Q., & Baig, M. S. (2017). Matrix metalloproteinases (MMPs) in liver diseases. Journal of Clinical and Experimental Hepatology, 7(4), 367-372. doi:10.1016/j.jceh.2017.09.004 |
| Abstract: | Matrix metalloproteinases (MMPs) are proteinases capable of degrading components of the extracellular matrix and numerous nonmatrix proteins. MMPs along with tissue inhibitors of MMPs, have been implicated in the pathogenesis of liver diseases. Although, the precise mechanism-of-actions of MMPs in various liver related disorders is largely unknown, however, data from diverse experimental models indicate that these proteinases influence cellular activities including proliferation and survival, gene expression, as well as multiple aspects of inflammation. Hence, MMP's are likely key players in the outcomes related to liver disease. © 2017 INASL |
| URI: | https://doi.org/10.1016/j.jceh.2017.09.004 https://dspace.iiti.ac.in/handle/123456789/4036 |
| ISSN: | 0973-6883 |
| Type of Material: | Review |
| Appears in Collections: | Department of Biosciences and Biomedical Engineering |
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