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| Title: | AIE active piperazine appended naphthalimide-BODIPYs: photophysical properties and applications in live cell lysosomal tracking |
| Authors: | Mobin, Shaikh M. |
| Keywords: | boron derivative;fluorescent dye;naphthalimide derivative;piperazine derivative;chemical structure;chemistry;fluorescence;HeLa cell line;human;light;lysosome;metabolism;pH;radiation response;spectrofluorometry;synthesis;Boron Compounds;Fluorescence;Fluorescent Dyes;HeLa Cells;Humans;Hydrogen-Ion Concentration;Light;Lysosomes;Molecular Structure;Naphthalimides;Piperazines;Spectrometry, Fluorescence |
| Issue Date: | 2019 |
| Publisher: | Royal Society of Chemistry |
| Citation: | Dwivedi, B. K., Singh, R. S., Ali, A., Sharma, V., Mobin, S. M., & Pandey, D. S. (2019). AIE active piperazine appended naphthalimide-BODIPYs: Photophysical properties and applications in live cell lysosomal tracking. Analyst, 144(1), 331-341. doi:10.1039/c8an01390j |
| Abstract: | Piperazine appended naphthalimide-BODIPYs (NPB1-NPB4) exhibiting solvatochromism and aggregation-induced emission with a large Stokes shift (up to 146 nm) have been described. Separation of naphthalimide and BODIPY fluorophores by piperazine in these conjugates creates a donor-acceptor system and induces twisted intramolecular charge transfer, in addition to photoinduced electron transfer. The crucial role of naphthalimide, the alkyl chain length, the piperazine ring, and the solid-state packing on AIE has been extensively investigated by various studies. Superior cell permeability coupled with bio-compatibility of these conjugates offers a unique opportunity for their potential applications in live cell lysosomal tracking. © The Royal Society of Chemistry. |
| URI: | https://doi.org/10.1039/c8an01390j https://dspace.iiti.ac.in/handle/123456789/8942 |
| ISSN: | 0003-2654 |
| Type of Material: | Journal Article |
| Appears in Collections: | Department of Chemistry |
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