Please use this identifier to cite or link to this item: https://dspace.iiti.ac.in/handle/123456789/9067
Title: High-yield graphene produced from the synergistic effect of inflated temperature and gelatin offers high stability and cellular compatibility
Authors: Tiwari, Pranav
Kaur, Navpreet
Mobin, Shaikh M.
Keywords: biomaterial;gelatin;graphite;chemical phenomena;chemistry;colloid;drug effect;erythrocyte;HeLa cell line;hemolysis;human;pH;synthesis;temperature;ultrasound;Biocompatible Materials;Colloids;Erythrocytes;Gelatin;Graphite;HeLa Cells;Hemolysis;Humans;Hydrogen-Ion Concentration;Hydrophobic and Hydrophilic Interactions;Sonication;Temperature
Issue Date: 2018
Publisher: Royal Society of Chemistry
Citation: Tiwari, P., Kaur, N., Sharma, V., & Mobin, S. M. (2018). High-yield graphene produced from the synergistic effect of inflated temperature and gelatin offers high stability and cellular compatibility. Physical Chemistry Chemical Physics, 20(30), 20096-20107. doi:10.1039/c8cp02263a
Abstract: The direct exfoliation of graphite (Gr) is highly desirable and feasible compared to conventional processes owing to its non-oxidative, facile and controlled synthesis conditions. Herein, gelatin (gel), a hydrolysed form of collagen, was used as an exfoliant to directly exfoliate Gr. The main advantages of exploring gel as an exfoliant is its easy availability, low cost and high biocompatibility, which alleviate the drawbacks of previous exfoliation methods. The effect of the exfoliation parameters such as temperature, ratio of interacting species and pH of the solution offers a high yield of graphene (G) with the added advantages of good solubility, easy dispersibility and high stability. The temperature elevation caused by the dissipation of sonic waves facilitates a high exfoliation yield. Yield of 4.37 mg mL-1 of G was achieved under the conditions of 7 h sonication at 60 °C, pH 7 and Gr to gel ratio of 60:40, whereas yield of 1 mg mL-1 was achieved under sonication at 30 °C. Raman spectroscopy and transmission electron microscopy indicated the production of G sheets with 3-5 layers. The adsorption of gel on the surface of G via π-π interactions offers high stability and retains its inherent crystallinity. The as-synthesized G dispersion exhibits good cyto- and hemocompatibility. Unlike graphene oxide, the G dispersion does not affect RBCs at a relatively high concentration of 10 mg mL-1. These findings offer new avenues for the large-scale production of G and promote its biomedical applications, particularly in scaffold materials and intravenous drug delivery. © the Owner Societies 2018.
URI: https://doi.org/10.1039/c8cp02263a
https://dspace.iiti.ac.in/handle/123456789/9067
ISSN: 1463-9076
Type of Material: Journal Article
Appears in Collections:Department of Chemistry

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