Please use this identifier to cite or link to this item:
https://dspace.iiti.ac.in/handle/123456789/9209
| Title: | Access to 4,6-Diarylpicolinates via a Domino Reaction of Cyclic Sulfamidate Imines with Morita-Baylis-Hillman Acetates of Nitroolefins/Nitrodienes |
| Authors: | Majee, Debashis Biswas, Soumen Mobin, Shaikh M. Samanta, Sampak |
| Keywords: | Rate constants;Reaction kinetics;Aryl rings;Chemical yields;Domino reactions;Imidazo[1 ,2-a]pyridine;Morita-baylis-hillman;Nitroolefins;Organic base;Synthetic strategies;Nitrogen compounds;1,4 diazabicyclo[2.2.2]octane;4,6 diarylpicolinate derivative;acetic acid derivative;aldehyde;alkadiene;alkene;imidazo[1,2 a]pyridine derivative;imine;nitrodiene derivative;nitroolefin derivative;nucleophile;organic compound;pyridine derivative;unclassified drug;Article;biological activity;chemical analysis;chemical modification;chemical reaction;chemical structure;domino reaction;one pot synthesis;physical chemistry;synthetic biology |
| Issue Date: | 2016 |
| Publisher: | American Chemical Society |
| Citation: | Majee, D., Biswas, S., Mobin, S. M., & Samanta, S. (2016). Access to 4,6-diarylpicolinates via a domino reaction of cyclic sulfamidate imines with morita-baylis-hillman acetates of Nitroolefins/Nitrodienes. Journal of Organic Chemistry, 81(10), 4378-4385. doi:10.1021/acs.joc.6b00472 |
| Abstract: | An interesting domino reaction of 5-membered cyclic sulfamidate imines with a variety of Morita-Baylis-Hillman acetates of nitroolefins/nitrodienes in the presence of DABCO as an organic base at 55 °C is reported for the first time. This new synthetic strategy provides a series of pharmacologically interesting 4,6-diarylpicolinates in high to excellent yields and allows several compatible functionalities on aryl rings. Moreover, the biologically interesting imidazo[1,2-a]pyridine (alpidem derivative) has been prepared in high chemical yield through a unique procedure. © 2016 American Chemical Society. |
| URI: | https://doi.org/10.1021/acs.joc.6b00472 https://dspace.iiti.ac.in/handle/123456789/9209 |
| ISSN: | 0022-3263 |
| Type of Material: | Journal Article |
| Appears in Collections: | Department of Chemistry |
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
Altmetric Badge: