Design, synthesis and characterization of tricarboxyamides

Abstract

Benzene1,3,5-tricarboxamides (BTAs) have become interesting structural entities in a wide range of scientific disciplines which are showed various applications in the area of nanotechnology, polymer processing and biomedical research. We report in this project, the synthesis of BTA based two peptides named as compound 1 (2-{3,5- Bis-[carboxy-2-(4-hydroxyl-phenyl)ethylcarbamoyl] benzoylamino}- 3-(4-hydroxyl-phenyl)-propionic acid) and compound 2 (2-{3,5-Bis[1- carboxyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-benzoylamino}-3-(1Hindol- 3-yl) propionic acid). Various spectroscopic techniques were used to characterize the reported compounds 1 and 2 such as 1H NMR, 13C NMR, FT-IR, TGA, UV-Vis, Fluorescence, Elemental analysis and Mass spectrometry.